Description

Journal of Toxicological Studies (JTS, eISSN: 3029-2832) serves as a vital academic platform for researchers, practitioners in the field of toxicology. By publishing high-quality articles that include original research, comprehensive reviews, and perspectives, JTS strives to disseminate knowledge related to the assessment and management of medicial toxicology or chemical hazards. The journal is committed to fostering scientific discourse and innovation in toxicological research, making it an essential reference for those dedicated to understanding and mitigating the impacts of toxins in various environments.

Latest Articles

  • Open Access

    Article

    Article ID: 1570

    Prevalence and impact of dye adulteration in toffee consumption: A case study on mildly acute or acute toxicity affecting the population in misbranded toffee and candy consumption; an occupational health study report and branding strategies in marketing new products

    by Saurabh Dilip Bhandare

    Journal of Toxicological Studies, Vol.3, No.1, 2025;

    Advancements in toxicological research have led to the development of several innovative methods for assessing the safety and potential risks of chemicals and toxic substances. This study investigates the prevalence and health implications of dye adulterants in toffees in excess amount from various brands distributed during a corporate year-end evaluation in Navi Mumbai, New Bombay 2015. The research employs random and stratified sampling methodologies to ensure a comprehensive analysis of the market. Laboratory tests reveals that dye X is present in 100% of samples from each brand, contradicting the natural flavour labels. Descriptive statistics indicate variations in dye concentration among brands, and ANOVA results demonstrate statistically significant differences in mean dye concentrations. Despite the presence of dye X across all brands, the chi-square test does not show a significant association between dye presence and brand at a 0.05 significance level. Employees reported adverse health effects, including dysuria, fatigue, and cardiovascular disturbances, after consuming the toffees, and tea. These findings highlight the need for stringent regulatory measures and consumer awareness to ensure food safety and mitigate health risks associated with food dye adulteration. The primary focus of this research study was to advance new methodologies for health monitoring and toxicology analysis that minimise large-scale disruptions. It aimed to foster innovation in medical science and establish new, documented methods for healthcare practitioners and professionals. These methods are designed to comprehensively analyse and document toxic events and systematically record data, enhancing the ability to manage and understand toxicological risks in a more controlled and efficient manner.

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  • Open Access

    Article

    Article ID: 2216

    Assessment of heavy metal contaminations in irrigation water, soils, and onions in the Isser and Zemmouri Regions, Algeria

    by Younes Mohamed Aksouh, Amal Rabahi, Nadjib Benosmane

    Journal of Toxicological Studies, Vol.3, No.1, 2025;

    This study investigates heavy metal contamination in irrigation water, soil, and onion (Allium cepa L.) samples from the Isser and Zemmouri regions of Boumerdes, Algeria, to assess potential health risks from consuming these vegetables. The analysis focused on both essential and toxic heavy metals, including iron (Fe), copper (Cu), zinc (Zn), cadmium (Cd), chromium (Cr), lead (Pb), and nickel (Ni). Atomic Absorption Spectroscopy (AAS) was employed for accurate quantification, and results were compared with FAO/WHO 2001 standards. Elevated copper (0.72 mg/L) and zinc (0.19 mg/L) levels were detected in Isser’s irrigation water, while Zemmouri’s water contained near-threshold concentrations of nickel (0.18 mg/L), chromium (0.09 mg/L), and copper (0.14 mg/L). Soil contamination was observed at both sites, with Isser showing high Cu (68.41 mg/kg), Zn (62.12 mg/kg), and Pb (71.63 mg/kg) levels, while Zemmouri exceeded limits for Pb (64.32 mg/kg) and Ni (11.21 mg/kg). In onion bulbs, Isser showed elevated chromium (3.1 mg/kg) and lead (0.31 mg/kg), while Zemmouri exhibited high zinc (11.34 mg/kg) and iron (43.76 mg/kg) levels in leaves. These findings indicate significant health risks associated with onion consumption from these regions, highlighting the need for improved monitoring and management of water quality and agricultural practices.

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  • Open Access

    Article

    Article ID: 1924

    Impact of salinity on density and mechanical strength of Avicennia germinans wood exposed to marine oil pollution in the Gabon Estuary

    by Mabicka Iwangou Saint Bickolard, Safou Tchiama Rodrigue, Besserer Arnaud, Andzi Barhé Timoléon, Gérardin Philippe

    Journal of Toxicological Studies, Vol.3, No.1, 2025;

    Located at the interface between land and sea, mangroves develop both near the sea and inland. However, mangroves that develop inland have to cope with variable, high salinity; and urban pollution, as is the case with the mangroves of the Ambowé lagoon in Greater Libreville. Salinity is an important parameter for mangrove growth. The aim of this work was; yes itto show the impact of salinity on the density and mechanical strength of A. germinans wood exposed to hydrocarbon pollution. To this end, wood samples taken from the polluted Ambowé site were analyzed in the laboratory for wood and physical-mechanical properties. The data obtained were compared with wood samples taken from the unpolluted Oveng site, which has a higher salinity. The results show that for the polluted wood showed wider rings, lower wood density and mechanical strength with values of 0.91 ± 0.05 and 70.28 MPa, respectively. Also, the rings and vessels of Oveng wood are narrower than those of Ambowé wood. These differences are linked to salinity. Salinity therefore affects the density and mechanical strength of A. germinans wood exposed to hydrocarbon pollution.

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  • Open Access

    Article

    Article ID: 1798

    The evolution of the EFSA OpenFoodTox database

    by Nadia Iovine, Alessandra Roncaglioni, Luca Sartori, Chihae Yang, Emilio Benfenati

    Journal of Toxicological Studies, Vol.3, No.1, 2025;

    Since its establishment in 2002, the European Food Safety Authority (EFSA) has been providing independent scientific advice on risks associated with the food chain. This manuscript provides a description of EFSA’s chemical hazards database OpenFoodTox (OFT), future perspectives and activities. OFT aims at mapping all the hazard identification and characterisation data that have been published in outputs from EFSA throughout the years. To date, OFT contains data for more than 5700 chemical substances in the food/feed chain. In line with the One Substance-One Assessment approach as part of the Chemicals Strategy for Sustainability, EFSA aims to further improve data quality and interoperability of OFT with IUCLID 6 and the EU Common Data Platform on Chemical Safety. To enhance its usability as a supporting tool for risk assessment activities, OFT will be migrated to IUCLID 6. More data will be collected and added to OFT, including endpoints related to in vitro assays, non-critical effects and exposure values. Furthermore, new in silico models (e.g., tools for read-across and grouping) will be developed based on the data already present in OFT for chemicals and endpoints that have been tested, with the aim of estimating the corresponding properties for the untested chemicals and endpoints.

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  • Open Access

    Perspective

    Article ID: 1970

    Risk assessments of contaminants of environmental concern need to address future scenarios to effectively protect human health and ecosystems

    by Denis Moledo de Souza Abessa

    Journal of Toxicological Studies, Vol.3, No.1, 2025;

    This article intends to discuss some limitations of the current approaches used to assess human health and environmental risks caused by contaminants of emerging concern (CECs). Human health and environmental risk assessments of CECs are normally based on a relationship between measured and predicted environmental concentrations (MECs and PECs, respectively) often estimated based on past conditions, and the respective predicted no-effect concentrations (PNECs). However, for most of chemicals, emissions continue to increase following the population growth and increasing polluting activities, resulting in a continuous rise of contaminants concentrations in the environmental compartments and the consequent increase of risks associated with them. Therefore, risk predictions based on past data may be unreliable and ineffective to support actions aimed to protect the environment, particularly in developing countries where pollutants monitoring are lacking or regulations are based on few academic studies. In this context, new tools need to be incorporated to improve the risk assessment protocols. Projections of future scenarios may predict the environmental concentrations of chemicals, allowing decision makers to establish appropriate actions to control the emissions and avoid the emergence of risks to human health and ecosystems before critical conditions are achieved. Thus, effective policies to control pollution and its effects would be taken.

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  • Open Access

    Article

    Article ID: 1660

    Physico-chemical characterization of a low cost biosorbent for efficient sequestration of heavy metals

    by Vimala Kumari Nagendra Prasad Meena Devi

    Journal of Toxicological Studies, Vol.3, No.1, 2025;

    Heavy metal pollution from industrial effluents poses significant environmental and public health challenges, particularly in aquatic ecosystems. Traditional wastewater treatment methods, are effective but often expensive, labor-intensive, and generate hazardous waste. Biosorption, using biological materials, presents a cost-effective and environment friendly alternative for heavy metal removal. The present study investigates the potential of Madhuca indica oil cake, a by-product of oil extraction can be used as a biosorbent for heavy metal sequestration. The oil cake was characterized by its physicochemical properties, including specific gravity (1.298 g/cm3), bulk density (0.66184 kg/m3), moisture content (11.34%), and dry matter content (88.66%). These properties suggest the oil cake is dense, nutrient-rich, and easy to handle and store. Fourier Transform Infrared (FTIR) spectroscopy was used to analyze the functional groups in the oil cake before and after drying at 105 °C. The results showed minimal changes in the chemical composition, with a slight shift in peak intensities indicating concentration effects due to drying. This stability is crucial for applications requiring intact bioactive compounds. The study highlights the versatility of Madhuca indica oil cake for multiple uses, including animal feed, fertilizer, and biomass for bioenergy. Furthermore, its potential as a biosorbent for heavy metal removal underscores its promise for environmental remediation. The study concludes that further research could optimize the utilization of Madhuca indica oil cake in agriculture and pollution control, contributing to sustainable environmental management.

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Announcements

Studies on microplastics featured in Nature and Journal of Toxicological Studies highlight their adverse impacts on health

2024-10-14

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Plastics have become ubiquitous in every facet of human daily life, and those with a particle size of less than 5mm are termed microplastics. These microplastics are readily ingested by living organisms and eventually make their way into the human body through the food chain. Not only are these minuscule plastic particles pervasive in soil, seas, and air, but they also represent an environmental issue that is increasingly demonstrating its severity. Moreover, they have infiltrated human bodies, posing a significant threat to human health.

Read more about Studies on microplastics featured in Nature and Journal of Toxicological Studies highlight their adverse impacts on health