The planetary ball milling of different powders yields similar granulometry

Clarissa  Ciarlantini; Antonella  Piozzi; Sergio  Ammendola

doi:10.59400/nmm2466

Clarissa Ciarlantini Department of Chemistry, Sapienza University of Rome, Rome 00185, Italy
Antonella Piozzi Department of Chemistry, Sapienza University of Rome, Rome 00185, Italy
Sergio Ammendola Ambiotec di SA via Appia Nord 47, 04012 Cisterna di Latina, Italy

Article ID: 2466

DOI: https://doi.org/10.59400/nmm2466

Keywords: ball milling; DLS; nanoparticles; nutraceuticals; top-down method

Abstract

The main objectives of nanotechnology include the establishment of processes for the development and control of the nanoparticles’ size and shape. Bottom-up or top-down methods can be used to achieve these objectives, but independently various parameters such as rotational speed, temperature, revolution time, and others must be controlled. However, both methods can be expensive, especially from an industrial point of view. To reduce production costs, we have investigated the feasibility of applying an identical top-down process to compounds with different chemical and physical properties. Starting from powders with very variable particle size, we arrive at powders with a particle size practically indistinguishable from the point of view of pharmaceutical technology. This procedure can be useful in industrial preparations.

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