Experiments should be carried out following the laws and regulations of the Ethics Committee affiliated with the author's institution. All studies using human or animal subjects should include an explicit statement in the Material and Methods section identifying the review and ethics committee approval for each study, if applicable. The statement will be displayed in the final publication. An Informed Consent Form should be obtained for all clinical treatment where disclosure is required regarding medical information, that includes discussion on the risks, benefits, and alternatives.
Academic Publishing Pte. Ltd. adheres to the guidelines of Ethical Oversight in COPE, and the Editor-in-Chief will oversee all the editorial process to ensure the objectivity, fairness and integrity of the academic scientific works. If human subjects are vulnerable groups, please obtain their guardian's written informed consent according to the Human & Animal Research Policy. All the peronal information will be considred to be confidential data, and it will not be used for commercial purposes.
Appeals and complaints
Academic Publishing Pte. Ltd. adopts a zero-tolerance policy concerning any misconduct and will aggressively address allegations from authors and readers. Allegations can be related to dissatisfaction with editorial decisions or the publishing process, and complaints about publishing ethics. Appeals and complainants could direct all correspondence to editorial_office@acad-pub.com. Information about the article and the specific reason for the complaint or appeal needs to be provided in detail. The Editorial Office will deal with it according to the procedure set out by COPE. An investigation team will be formed upon receipt of a complaint or appeal, and make a final decision based on conclusive evidence. Complainants will be informed of the decision and there are 14 days for them to appeal against the decision, except for decisions on appeals against editorial decisions.
Academic Publishing insists on taking academic exchange and publication as the main line, carrying out comprehensive management based on science and technology, and fully exploring excellent international publishing resources. Within 5 years, it will form a strategic framework and scale with science (S), technology (T), medicine (M), education (E), and humanities and arts (H) as the main publishing fields. Academic Publishing is headquartered in Singapore and based in Malaysia, with the United States and China providing the main scientific and academic resources. At the same time, it has established long-term good cooperative relations with other publishing companies, scientific research communities, and academic organizations in more than a dozen countries and regions. Academic Publishing uses English and Chinese as its main publishing languages, mainly publishing books, journals, and conference papers in print and online. The vast majority of publications follow the international open access policy, providing stable and long-term quality and professional publications. With the joint efforts of the expert team and our professional editorial team, our publications will gradually be indexed by international databases in stages to provide convenient and professional retrieval for various scholars. At the same time, manuscripts we accept will be subject to the peer review principle, and cutting-edge and innovative research articles will be preferentially accepted for peer reference and discussion. All kinds of our publications are welcome for peer to contribute, access, and download.
Insecticides represent the most used control method against the insect pests of stored food products. But there are strains of insects which are resistant to these insecticides: it is the case of the beetle of the chickpea Callosobruchus maculatus . The present study has for objective the evaluation of the biological activity of chitinolytic enzymes extracted from the fish offals Scorpaena scrofa (scorpion fish) on this beetle at different doses (3%, 6%, 9%, 12%, 15% and 21%) prepared with the buffer solution. The results obtained from three treatments (T 1 , T 2 and T 3 ) realized according to the dose of the crude enzyme and the time of exposure were compared with those of the controls and have showed a very significant efficiency of our crude enzyme on the reduction of the fertility rate of 100% by treating the couple (T 1 ) at the same time as to treat the male (T 3 ) and the female (T 2 ) separately with the strongest dose (21%) for 48 h of exposure. It would be thus desirable to demonstrate the activity of these enzymes in the real conditions of storage.
Na + -K + -ATPase is a membrane bound enzyme responsible for the transport of ions through the membrane and immediate release of energy. This enzyme is known to be an early target for oxygen radical induced damage to intact cell. Exposure of C. punctatus to subacute concentrations of lindane for 96 h caused significant reduction in the activities of Na + -K + -ATPase in all the tissues of the fish tested; brain being maximally affected and the heart being least affected organ at the highest concentration of lindane (0.1 mg/L). The effect of pesticide was concentration dependent. The percent decrease in the activity of Na + -K + -ATPase in brain, gills, heart, kidney, liver and muscle was found to be 36.7, 23.4, 19.2, 29, 22.9 and 29.7, respectively. The order of level of enzyme activity recorded was as following: liver > gills > kidney > brain > muscle > heart in the control.
Due to the ubiquitous occurrence in the aquatic environment and terrestrial ecosystem and underlying eco-environmental risks, nano/microplastics (NPs/MPs) have sparked great public concerns. The purpose of this work is aimed to summarize the harmful influence of NPs/MPs on reproduction and offspring health and further explore the potential mechanisms of action, thereby facilitating the more comprehensive understanding of NPs/MPs features. Literature search databases included EMBASE, Web of Science, and PubMed. The study selection and data extraction were implemented according to the inclusion criteria. NPs/MPs could accumulate and trigger reproductive toxic responses and thereafter generate deleterious effects on the offspring health. Accordingly, the reproductive toxicity of NPs/MPs was characterized as the sperm deformity, decline in sperm count and motility, follicular growth tardiness, ovarian fibrosis, granulosa cell death, disorder of reproductive hormone secretion, as well as the fetal growth restriction, glycolipid metabolism disorder, and inflammatory responses of the next generation. Additionally, mechanism research revealed that NPs/MPs exposure brought about inflammatory responses and oxidative stress and thereafter, destroyed the blood-testis barrier (BTB) integrity, motivated spermatogenic cell apoptosis by activating the JNK and p38/MAPK-Nrf2/NF-κB pathways, and induced ovarian granulosa cell pyroptosis and apoptosis and subsequent ovarian fibrosis via the Wnt/β-Catenin and NLRP3/Caspase-1 pathways. Nevertheless, this work also highlighted the imperative requirements for scientific and systematic risk assessments of NPs/MPs, so as to identify the feasible risk mitigation strategies.