Academic Publishing insists on taking academic exchange and publication as the main line, carrying out comprehensive management based on science and technology, and fully exploring excellent international publishing resources. Within 5 years, it will form a strategic framework and scale with science (S), technology (T), medicine (M), education (E), and humanities and arts (H) as the main publishing fields. Academic Publishing is headquartered in Singapore and based in Malaysia, with the United States and China providing the main scientific and academic resources. At the same time, it has established long-term good cooperative relations with other publishing companies, scientific research communities, and academic organizations in more than a dozen countries and regions. Academic Publishing uses English and Chinese as its main publishing languages, mainly publishing books, journals, and conference papers in print and online. The vast majority of publications follow the international open access policy, providing stable and long-term quality and professional publications. With the joint efforts of the expert team and our professional editorial team, our publications will gradually be indexed by international databases in stages to provide convenient and professional retrieval for various scholars. At the same time, manuscripts we accept will be subject to the peer review principle, and cutting-edge and innovative research articles will be preferentially accepted for peer reference and discussion. All kinds of our publications are welcome for peer to contribute, access, and download.
Vol. 1 No. 1 (2023)
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Open AccessReview
Article ID: 270
Cordyceps at a glance: Miraculous metabolite and molecular insightsby Loknath Deshmukh, Rupesh Thakur, Aanchal Sonkuwar, Sardul Singh Sandhu
Metabolism Studies, Vol.1, No.1, 2023; 161 Views, 99 PDF Downloads
As an entomopathogenic fungus with significant pharmacological and therapeutic implications, particularly for human health, Cordyceps sp. is a good alternative for ethnopharmacological use. A unique bio-metabolite termed Cordycepin (3′deoxyadenosine), which has extremely significant anti-cancer, anti-oxidant, and anti-inflammatory properties, is the main component of the extract made from this fungus. Due to their diverse biological functions, Cordyceps fungi have long drawn the interest of scientists; nonetheless, it has been difficult to successfully isolate active monomer molecules from them. Fungi produce significantly fewer substances in the lab than they do in the wild. In this review, I go through recent discoveries about the transcriptional and epigenetic control of BGCs as well as the ecological functions of fungal secondary metabolites in development, defense, and warfare. I also look at ways to find new fungal metabolites and the difficulties associated with gathering secondary metabolites derived from fungi. Metabolites serve a variety of purposes, including energy production, structural support, signaling and modulation of enzyme activity (often as an enzyme cofactor), defense, and interactions with other organisms (such as the production of pigments, odorants, and pheromones). Refocusing and reviving efforts to mine the fungal secondary metabolome has been one of the most interesting developments in the field of microbiology. Cordyceps sp., an entomopathogenic fungus, is a potential ethnopharmacological source due to its unique bio-metabolite, Cordycepin, which has anti-cancer, anti-oxidant, and anti-inflammatory properties. Its potential applications include immune system effects, DNA technology, metagenomics, kidney and cardiovascular systems, and cancer prevention in food and cosmetic industries.
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Open Access
Review
Article ID: 1193
Bio-Metabolomic odyssey: Deciphering the antimicrobial armamentarium of Endophytic Fungi in Anogeissus latifolia and related Sps. for therapeutic advancementsby Vibhuti Sabhlok, Pavan Jain, Shama J. P. Khanam, Aanchal Sonkuwar, Sardul Singh Sandhu, Loknath Deshmukh
Metabolism Studies, Vol.1, No.1, 2023; 114 Views, 118 PDF Downloads
The review presents a comprehensive overview of the potential therapeutic advancements facilitated by microbial metabolites, particularly focusing on the symbiotic relationship between endophytic fungi and Anogeissus latifolia and related species. These fungi produce a diverse array of metabolites with pharmacological significance, including antibacterial, anticancer, antioxidant, and anti-diabetic properties. The review highlights the importance of endophytic fungi in natural drug discovery, emphasizing their role in enhancing plant resilience and producing therapeutically relevant compounds. Chemical analysis of A. latifolia reveals compounds like ellagic acid derivatives and flavonoids with medicinal potential, while pharmacological investigations showcase the plant’s efficacy in traditional applications and its promising antibacterial properties. Methodologies for identifying and characterizing bioactive compounds, such as metabolomics and high-performance thin chromatography, are outlined, supporting the hypothesis that undiscovered bio-metabolites from endophytic fungi hold high antibacterial potential, thus offering new avenues for drug discovery. In conclusion, the exploration of microbial metabolites, particularly those derived from endophytic fungi in A. latifolia, presents promising opportunities for developing novel, environmentally friendly, and effective therapies. This review underscores the significance of A. latifolia in herbal medicine and drug discovery, emphasizing the importance of preserving biodiversity and sustainable resource utilization.
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Open Access
Editorial
Article ID: 150
Electrolyzed hydrogen water and photobiomodulation therapy have several features in commonby Michael R. Hamblin
Metabolism Studies, Vol.1, No.1, 2023; 121 Views, 165 PDF Downloads
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