Vol. 3 No. 1 (2023)

  • Open Access

    Articles

    Article ID: 25

    Research Progress of Photothermal Nanomaterials and Bioreaction Degradation Mechanism in Cancer Therapy

    by Jia Liu, Minghua Wu

    Ecomaterials, Vol.3, No.1, 2023;

    Abstract: Photothermal therapy (PTT) is an alternative new cancer treatment after surgery, radiotherapy and chemotherapy. Thinking about the characteristics of tumor photothermal therapy, the key factors of photothermal nanomaterials in clinical applications include theire photothermal conversion efficiency, surface modification activity, biocompatibility, biodegradability and low toxicity. With the development of photothermal nanomaterials, PTT holds immense potential in clinical translation. Up to now, four generation of photothermal nanomaterials have been developed, including noble metal nanoparticles, carbon based nanomaterials, metal and non-metallic compound nanomaterials and organic dyes.

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  • Open Access

    Articles

    Article ID: 26

    Ecological building material in glass, sand and polyplastics (vapoli)

    by Delma Esther Rocha Alvarez, Carol Pérez, Jorge Villanueva

    Ecomaterials, Vol.3, No.1, 2023;

    Abstract: This article refers to the development of a new environmentally friendly construction material; it mentions concepts of contamination in Colombia where the lack of reuse of recyclable materials is demonstrated with figures, and states its objectives and justification according to the needs or deficiencies outlined in the document. In the research, studies of similar models are carried out where research related to the proposed topic is shown; likewise, articles and national and international laws that support this work are evoked.

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  • Open Access

    Articles

    Article ID: 27

    Study on biomimetic phospholipid modification of aliphatic polyester biomaterials

    by Xiaomin ZHANG, Jin DENG

    Ecomaterials, Vol.3, No.1, 2023;

    Abstract: It is low feasibility using plasma energy particles to excite, ionize and break bonds molecules on the surface of aliphatic polyester biomaterials to produce new topological structures. The biomimetic phosphatidylcholine modification technology of aliphatic polyester biomaterials was studied. The phosphatidylcholine monomer [2 (methacryloxy) ethyl]phosphatidylcholine was synthesized by reaction of 2 chloro 1, 3, 2 dioxaphosphoric heterocyclic pentane with different raw material solutions; the phosphatidylcholine[2 (methacryloxy) ethyl]phosphatidylcholine, acrylonitrile and water were copolymerized to form PANCMPC; the phosphatidylcholine [2 (methacryloxy) ethyl]phosphatidylcholine was replaced by PANCMPC, and PANCHEMA was obtained by repeated copolymerization. PANCHEMA was reacted with 2 chloro 2 oxygen 1, 3, 2 dioxophosphorus heterocyclic pentane, and then opened with trimethylamine to form biomimetic phospholipid modified PLCANCP. Experiments show that the proposed technology has good hydrophilicit

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  • Open Access

    Articles

    Article ID: 17

    Experimental study of new bionic bone in repairing goat skull defects

    by Cui WANG, Xiuqing QIAN

    Ecomaterials, Vol.3, No.1, 2023;

    Objective In order to verify the biological safety and the effect of inducing osteogenesis of two different proportions of collagen based biomimetic bone materials, the model of goat skull defect was designed. Methods First, we used trephine to make circular defect in goat skull, then the bionic bones with different proportions of collagen were implanted into the defect areas. Finally, the inflammatory response and osteogenesis in the bone defect areas were observed after implantation. Results Most of the A group materials with high collagen content were mostly degraded and partly induced into bone, while the B group with low collagen content was not degraded and had no effect on bone formation. After the two groups of materials were implanted into the goats, there were no inflammatory reactions, which meant that the collagen based biomimetic bone material had good biocompatibility. Conclusions The collagen based biomimetic bone material has good biocompatibility, good biodegradability, and a certain effect on bone formation

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  • Open Access

    Articles

    Article ID: 18

    Effects of graphene/PLGA composite scaffolds on proliferation and differentiation of bone marrow mesenchymal stem cells

    by Ao Zheng, Lingyan Cao, yang Liu, Jiannan Wu, Xinquan Jiang

    Ecomaterials, Vol.3, No.1, 2023;

    Objective: This study aimed at fabricating three-dimensional porous graphene (G)/poly(lactic-co-glycolic acid (PLGA) composite scaffolds and establishing the potential for further application of G/PLGA porous scaffolds in bone tissue engineering. Methods: Different concentrations of graphene was mixed with PLGA (G/PLGA, wt. ‰: 0, 0.5‰, 5‰). Results: Scanning electron microscopy confirmed the inner connected porous structure of the three-dimensional G/PLGA scaffold as well as the uniform distribution of graphene in the scaf-folds. CCK-8 test indicated that G/PLGA porous scaffolds had no obvious cytotoxicity. Compared with BMSCs seeded on PLGA scaffold, the ALP activity of BMSCs seeded on the G/PLGA scaffolds increased and the expression of bone related genes was significantly up-regulated with increase of G concentration. G/PLGA porous scaffold containing 5‰ graphene showed more obvious effects on osteogenic differentiation. Conclusions: The G/PLGA three-dimensional porous scaffold prepared in this research possessed good biocom-patibility and could promote osteogenic differentiation of BMSCs in vitro. Thus, it has been expected to be used as a scaffold for bone tissue engineering.

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