https://ojs.acad-pub.com/index.php/MS Academic Publishing Pte. Ltd. en-US Metabolism Studies <p>Authors contributing to this journal agree to publish their articles under the<span> </span><a href="http://creativecommons.org/licenses/by/4.0" target="_blank">Creative Commons Attribution 4.0 International License</a>, allowing third parties to share their work (copy, distribute, transmit) and to adapt it <span lang="EN-US">for any purpose, even commercially, under the condition that the authors are given credit.</span> With this license, authors hold the copyright.</p><p><img src="https://esp.apacsci.com/public/site/images/reviewer/OIP-C.jpg" alt="" /></p> https://ojs.acad-pub.com/index.php/MS/article/view/270 <div>As an entomopathogenic fungus with significant</div><div>pharmacological and therapeutic implications, particularly for human</div><div>health, Cordyceps sp. is a good alternative for ethnopharmacological use.</div><div>A unique bio-metabolite termed Cordycepin (3′deoxyadenosine), which</div><div>has extremely significant anti-cancer, anti-oxidant, and</div><div>anti-inflammatory properties, is the main component of the extract</div><div>made from this fungus. Due to their diverse biological functions,</div><div>Cordyceps fungi have long drawn the interest of scientists; nonetheless, it</div><div>has been difficult to successfully isolate active monomer molecules from</div><div>them. Fungi produce significantly fewer substances in the lab than they</div><div>do in the wild. In this review, I go through recent discoveries about the</div><div>transcriptional and epigenetic control of BGCs as well as the ecological</div><div>functions of fungal secondary metabolites in development, defense, and</div><div>warfare. I also look at ways to find new fungal metabolites and the</div><div>difficulties associated with gathering secondary metabolites derived</div><div>from fungi. Metabolites serve a variety of purposes, including energy</div><div>production, structural support, signaling and modulation of enzyme</div><div>activity (often as an enzyme cofactor), defense, and interactions with</div><div>other organisms (such as the production of pigments, odorants, and</div><div>pheromones). Refocusing and reviving efforts to mine the fungal</div><div>secondary metabolome has been one of the most interesting</div><div>developments in the field of microbiology. Cordyceps sp., an</div><div>entomopathogenic fungus, is a potential ethnopharmacological source</div><div>due to its unique bio-metabolite, Cordycepin, which has anti-cancer,</div><div>anti-oxidant, and anti-inflammatory properties. Its potential</div><div>applications include immune system effects, DNA technology,</div><div>metagenomics, kidney and cardiovascular systems, and cancer</div><div>prevention in food and cosmetic industries.</div> Loknath Deshmukh Rupesh Thakur Aanchal Sonkuwar Sardul Singh Sandhu Copyright (c) 2023 Loknath Deshmukh, Rupesh Thakur, Aanchal Sonkuwar, Sardul Singh Sandhu https://creativecommons.org/licenses/by/4.0 2023-12-15 2023-12-15 1 1 https://ojs.acad-pub.com/index.php/MS/article/view/150 N/A Michael R. Hamblin Copyright (c) 2023 Michael R. Hamblin https://creativecommons.org/licenses/by/4.0 2023-09-14 2023-09-14 1 1