https://ojs.acad-pub.com/index.php/MS/issue/feed 2024-01-12T14:58:00+00:00 Manage Editor editorial-ms@acad-pub.com Open Journal Systems https://ojs.acad-pub.com/index.php/MS/article/view/270 2024-01-12T14:58:00+00:00 Loknath Deshmukh loknathd@itmuniversity.org Rupesh Thakur loknathd@itmuniversity.org Aanchal Sonkuwar loknathd@itmuniversity.org Sardul Singh Sandhu loknathd@itmuniversity.org

<div>As an entomopathogenic fungus with significant</div><div>pharmacological and therapeutic implications, particularly for human</div><div>health, Cordyceps sp. is a good alternative for ethnopharmacological use.</div><div>A unique bio-metabolite termed Cordycepin (3′deoxyadenosine), which</div><div>has extremely significant anti-cancer, anti-oxidant, and</div><div>anti-inflammatory properties, is the main component of the extract</div><div>made from this fungus. Due to their diverse biological functions,</div><div>Cordyceps fungi have long drawn the interest of scientists; nonetheless, it</div><div>has been difficult to successfully isolate active monomer molecules from</div><div>them. Fungi produce significantly fewer substances in the lab than they</div><div>do in the wild. In this review, I go through recent discoveries about the</div><div>transcriptional and epigenetic control of BGCs as well as the ecological</div><div>functions of fungal secondary metabolites in development, defense, and</div><div>warfare. I also look at ways to find new fungal metabolites and the</div><div>difficulties associated with gathering secondary metabolites derived</div><div>from fungi. Metabolites serve a variety of purposes, including energy</div><div>production, structural support, signaling and modulation of enzyme</div><div>activity (often as an enzyme cofactor), defense, and interactions with</div><div>other organisms (such as the production of pigments, odorants, and</div><div>pheromones). Refocusing and reviving efforts to mine the fungal</div><div>secondary metabolome has been one of the most interesting</div><div>developments in the field of microbiology. Cordyceps sp., an</div><div>entomopathogenic fungus, is a potential ethnopharmacological source</div><div>due to its unique bio-metabolite, Cordycepin, which has anti-cancer,</div><div>anti-oxidant, and anti-inflammatory properties. Its potential</div><div>applications include immune system effects, DNA technology,</div><div>metagenomics, kidney and cardiovascular systems, and cancer</div><div>prevention in food and cosmetic industries.</div>

2023-12-15T00:00:00+00:00 Copyright (c) 2023 Loknath Deshmukh, Rupesh Thakur, Aanchal Sonkuwar, Sardul Singh Sandhu https://ojs.acad-pub.com/index.php/MS/article/view/150 2024-01-12T14:58:00+00:00 Michael R. Hamblin hamblin.lab@gmail.com

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2023-09-14T15:42:12+00:00 Copyright (c) 2023 Michael R. Hamblin